Family-Based Multi-SNP X Chromosome Analysis Using Parent Information
نویسندگان
چکیده
منابع مشابه
Family-Based Multi-SNP X Chromosome Analysis Using Parent Information
We propose a method for association analysis of haplotypes on the X chromosome that offers both improved power and robustness to population stratification in studies of affected offspring and their parents if all three have been genotyped. The method makes use of assumed parental haplotype exchangeability (PHE), a weaker assumption than Hardy-Weinberg equilibrium (HWE). PHE requires that in the...
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2016
ISSN: 1664-8021
DOI: 10.3389/fgene.2016.00020